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Research Article Open access CC BY 4.0

Influenza and Respiratory Syncytial Virus in Hospitalized Patients with Acute Exacerbation of Severe COPD in Izmir, Turkey

Gulrü Erbay, Ceyda Anar, Gunes Senol, Can Bicmen, Yusuf Pinar, Melih Buyuksirin

Microbiology Research Journal International · pp. 459–465 · Published 8 Dec 2014

10.9734/BMRJ/2015/13251

Abstract

Aims: The aim of this study is documenting the presence of respiratory syncytial virus (RSV) and influenza virus infections in hospitalized patients with AE-COPD in autumn and winter months. Study Design: The study was designed as a prospective cohort study. Place and Duration of Study: September 2006 and February 2007, Izmir, Turkey. Methodology: Severe AE-COPD patients were studied by ready to use real time-PCR system and micro ELISA RSV and Influenza IGM and IgG antibody detection systems. Results: Fifty AE-COPD cases enrolled to the study. Influenza and RSV were detected in 13 (26%) and 12 (24%) patients, respectively. Seven (14%) bacterial agents (4 P. aeruginosa, 2 S. pneumoniae, 1 E. coli) were isolated from patients with viral infections. Conclusion: Influenza viruses and RSV are important causative viral agents of AE-COPD. PCR and serological methods were decided to be used together for diagnosis of viral AE-COPD.

COPD influenza PCR RSV serology

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