In vitro Antimicrobial and Antioxidant Analysis of Gallic Acid from the Leaves of Ludwigia abyssinica A. Rich
Olaoluwa Oyedeji, Festus O. Taiwo, Femi O. Ayinde, Olukayode S. Ajayi, Matthew Oziegbe, Monsuru T. Kelani, Adetola H. Adewole
European Journal of Medicinal Plants · pp. 1098–1112 · Published 13 Jun 2014
10.9734/EJMP/2014/7553Abstract
Aims: To evaluate the antimicrobial and antioxidant potentials of a biologically active compound isolated from the leaves of Ludwigia abyssinica A. Rich. Study Design: Antimicrobial and antioxidant analysis of compound from the n-butanol fraction of plant leaf. Place and Duration of Study: Chemistry and Microbiology Laboratories, Faculty of Science, Obafemi Awolowo University, Ile-Ife between November 2011 and September 2012. Methodology: Chromatographic and nuclear magnetic resonance techniques were used to isolate and characterize the biologically active compound, respectively. Disc diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) measurements were used for antimicrobial test. 1, 1-diphenyl-2-picrylhydrazyl hydrate (DPPH) radical scavenging assay was used for antioxidant test. Results: The phenolic compound, 3,4,5-trihydroxybenzoic acid, also known as gallic acid was isolated from the n-butanol fraction of L. abyssinica leaf. It showed broad spectrum antimicrobial activities with zones of inhibition in the range 26.67±1.53 to 32.00±1.00 mm for the test bacteria and 6.67±1.15 to 30.33±0.58 mm for the test fungal strains. MIC and MBC values for gallic acid ranged from 12.5 to 200 µg ml-1 and 50 to 400 µg ml-1, respectively, comparing favourably with the standard reference drug used. DPPH radical scavenging activity for the compound was IC50 = 9.38 µg ml-1 compared with IC50 = 27.08µg ml-1 obtained for the standard ascorbic acid. Conclusion: The results show that gallic acid from Ludwigia abyssinica leaves possesses In vitro antimicrobial and antioxidant properties and thus the plant has potentials as a source of natural health-giving products, given further investigations.
References (49)
- 1 Plant Products as Antimicrobial Agents [DOI]
- 2 Polyphenols: food sources and bioavailability [DOI]
- 3 Free Radicals, Antioxidants in Disease and Health [DOI]
- 4 Antioxidant Activity and Phenolic Compounds in Selected Herbs [DOI]
- 5 Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically : Approved standard
- 6 A Sensitive and Quick Microplate Method to Determine the Minimal Inhibitory Concentration of Plant Extracts for Bacteria [DOI]
- 7 Screening of radical scavenging activity of some medicinal and aromatic plant extracts [DOI]
- 8 Tannins and Human Health: A Review [DOI]
- 9 Polyphenols and disease risk in epidemiologic studies [DOI]
- 10 The Useful Plants of West Tropical Africa [DOI]
- 11 Antioxidants and Prevention of Chronic Disease [DOI]
- 12 Screening of 70 medicinal plant extracts for antioxidant capacity and total phenols [DOI]
- 13 Antioxidant Activity of Water Extract of Harng Jyur (Chrysanthemum morifolium Ramat) [DOI]
- 14 Antibacterial action of several tannins against Staphylococcus aureus [DOI]
- 15 Structure–activity relationship analysis of antioxidant ability and neuroprotective effect of gallic acid derivatives [DOI]
- 16 Polyphenols and antioxidant capacity of Bulgarian medicinal plants [DOI]
- 17 Antioxidant properties of several commercial mushrooms [DOI]
- 18 Martindale. The extra pharmacopoeia [DOI]
- 19 Antimicrobial activity of some medicinal plants of the island Soqotra [DOI]
- 20 Traditional Medicine Practice amongst the Igede People of Nigeria. Part II [DOI]
- 21 Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods [DOI]
- 22 Antimicrobial gallic acid from Caesalpinia mimosoides Lamk. [DOI]
- 23 A Modern Look at Folkloric Use of Anti-infective Agents [DOI]
- 24 Growing Problem of Multidrug-Resistant Enteric Pathogens in Africa [DOI]
- 25 Risks and benefits of commonly used herbal medicines in Mexico [DOI]
- 26 Ethno-medicinal study of plants used for treatment of human and livestock ailments by traditional healers in South Omo, Southern Ethiopia [DOI]
- 27 The Outer Membrane of Gram-Negative Bacteria Inhibits Antibacterial Activity of Brochocin-C [DOI]
- 28 Antimicrobial Ellagitannin of Punica granatum Fruits [DOI]
- 29 ANTIOXIDANT ACTIVITY OF MELISSA OFFICINALIS LEAVES [DOI]
- 30 Oenothein B's contribution to the anti-inflammatory and antioxidant activity of Epilobium sp [DOI]
- 31 In vitro antibacterial activity and acute toxicity studies of aqueous-methanol extract of Sida rhombifolia Linn. (Malvaceae) [DOI]
- 32 In vitro antioxidant properties of morphine [DOI]
- 33 Tolerance of Pseudomonas aeruginosa to Melaleuca alternifolia (tea tree) oil is associated with the outer membrane and energy-dependent cellular processes [DOI]
- 34 The Ethnomedicine of the Haya people of Bugabo ward, Kagera Region, north western Tanzania [DOI]
- 35 Biosynthesis of gallic acid in Rhus typhina: discrimination between alternative pathways from natural oxygen isotope abundance [DOI]
- 36 Isolation and antimicrobial activity of two phenolic compounds from Pulicaria odora L. [DOI]
- 37 The morphology, extractions, chemical constituents and uses of Terminalia chebula: A review [DOI]
- 38 Structure–activity relationships for the analgesic activity of gallic acid derivatives [DOI]
- 39 Inhibition of mutagenicity of a model nitrosation reaction by naturally occurring phenolics, coffee and tea [DOI]
- 40 Antitumor-promoting activities of hydrolyzable tannins in mouse skin [DOI]
- 41 Sexual reproduction of two alien invasive Ludwigia (Onagraceae) on the middle Loire River, France [DOI]
- 42 Antibacterial activity of Ludwigia adscendens [DOI]
- 43 Antitumor and antibacterial activity of ethylacetate extract of Ludwigia hyssopifolia linn and its active principle piperine.
- 44 Antibacterial, antifungal and phytochemical analysis of crude extracts from the leaves of Ludwigia abyssinica A. Rich. and Ludwigia decurrens Walter [DOI]
- 45 Antibacterial activity of gallic acid from the flowers of Rosa chinensis Jacq. against fish pathogens [DOI]
- 46 Inhibitory effects of antioxidant constituents from Melothria heterophylla on matrix metalloproteinase-1 expression in UVA-irradiated human dermal fibroblasts.
- 47 Systematics of Epilobium (Onagraceae) in China [DOI]
- 48 Impact of antimicrobial resistance on health outcomes in the out-patient treatment of adult community-acquired pneumonia: a probability model [DOI]
- 49 Royal Museum for Central Africa, Tervuren, Belgium. [DOI]
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