Immunohistochemical Analysis of Myofibroblasts Using α- SMA in Oral Submucous Fibrosis Turning into Malignancy- A Case Report and Review
Swapan Kumar Purkait, . Abhinandan, Nimisha Priya, Sriyanshi Singh, Sneha Singh
Journal of Pharmaceutical Research International · pp. 192–198 · Published 29 Nov 2021
10.9734/jpri/2021/v33i52A33575Abstract
Oral submucous fibrosis is a premalignant condition, characterized by fibrosis in oral mucosa causing stiffness of mucosa and leading to reduced mouth opening. The malignant transformation of oral submucous fibrosis is very high among the rest of the premalignant conditions. Chronic chewing of arecanut causes production of myofibroblasts. These myofibroblasts plays an important role in neoangiogenesis as well as disintegration of the basement membrane at the tumor invasive front leading to carcinoma. Here, we are doing an Immunohistochemical study using alpha SMA for proper microscopic visulizations of myofibroblastic activity in an OSF patient, encompassing the pathogenesis and malignant potentiality of the disease.
Cited by 0
No indexed citations yet.
Related research
- Odontogenic Keratocyst: A Case Series — shares topic coverage
- Oral Cancer and Oral Sex: Awareness and Practice among Nursing Students in Ibadan Metropolis, Nigeria — shares topic coverage
- Oral Candidiasis: Complication of Concomitant Chemo-radiotherapy in Patients with Oral Squamous Cell Carcinoma — shares topic coverage
- Evaluation of Candidal Species in Oral Submucous Fibrosis and Oral Lichen Planus: A Microbiological Study — shares topic coverage
- Awareness of the Oral Cancer Risk Factors in People from Nothern-Eastern Region of Poland — shares topic coverage
Article metrics
Real usage data collected on this platform.
6
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.