Hydroxicloroquine, What is the Role of the Drug in the Treatment of COVID-19? A Review
Eliza Miranda Ramos, Francisco José Mendes Dos Reis, Gilberto Gonçalves Facco, Emerson Luiz Lima Araújo, Igor Domingos de Souza, Glícia Caroline Andrade Ramos, Alessandro Carvalho da Fonseca, Iara Barbosa Ramos, Hugo Vieira Ramos, Valter Aragão Do Nascimento
Asian Journal of Research in Medical and Pharmaceutical Sciences · pp. 7–22 · Published 2 Jul 2020
10.9734/ajrimps/2020/v9i130142Abstract
Introduction: Coronaviruses (COVID-19) is an emerging virus with severe respiratory infection. Despite several efforts, so far there is no medicine to fight it and use it as the ideal treatment. OBJECTIVES: This study aims to describe the role of hydroxychloroquine in the treatment of patients with COVID-19 and thus present its benefits in the respective doses. Methodology: The methodology used was the systematic review with meta-analysis. Results: From the reading of the 75 papers found, only three articles were excluded for not presenting a complete abstract, 65 were excluded for not presenting eligibility according to the inclusion criteria, 01 was excluded for reaching a methodological score below 20 points in Down and Black (1998) and ending the process of inclusion of the articles, only 06 articles were included and included 894 patients. Conclusion: Despite the small number of published articles, this meta-analysis found that the use of hydroxychloroquine as an adjunct therapy in the follow-up of COVID-19 in patients with mild to severe clinical signs brings benefits and avoids hospitalization in intensive care.
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