Solvent-free Mechanochemical Synthesis, Characterization and Antibacterial Potency of CaO@SiO2 Nanocomposite
Danbature Wilson Lamayi, Mela Yoro, Zaccheus Shehu, Yakong David Madugu, Sani Ibrahim Aliyu
Journal of Materials Science Research and Reviews · pp. 536–542 · Published 28 Dec 2019
Abstract
Objectives: This aim of this study was to synthesized CaO@SiO2 nanocomposite using solvent-free mechanochemical method and applied against gram-positive bacteria (Bacillus subtilis, Klebsiella pneunoniae) and gram-negative bacteria (Pseudomonas aeruginasa, Escherichia coli, and Salmonella typhi). Methods: The structure of CaO@SiO2 nanocomposite was confirmed by FTIR and UV-Visible spectroscopy. Agar well diffusion method was used for the antibacterial studies. The antibacterial activity of CaO@SiO2 nanocomposite was found to be dose dependent. The zone of inhibition decreases in the following order; S. typhi, P. aeruginosa, K. pneumoniae, B. subtilis and E. coli. Conclusions: CaO@SiO2 nanocomposite showed excellent antibacterial activity and can be used as promising antibacterial agent.
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