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Research Article Open access CC BY 4.0

Pleural Effusion as Manifestation of IgG4 Related Disease

N. Kallel, N. Mahmoud, S. Charfi, N. Moussa, R. Gargouri, N. Bahloul, I. Yangui

Asian Journal of Case Reports in Medicine and Health · pp. 89–95 · Published 11 Jun 2021

Abstract

Immunoglobulin G4-related disease is a very rare and little known sclerosing inflammatory disease. This pathology has been reported in various organs. Of these, there are only 9  reports describing pleuritis as IgG4-related disease with no other organ involevement. We report the original observation of an isolated pleural effusion as manifestation of IgG4 related disease in a 60-year-old woman. We suggest the possibility to includ IgG4 related disease in the differential diagnosis of unexplained pleuritis. Our observation is distinguished by the isolated nature of pleural involvement and the spontaneous regression of pleural effusion.

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