Bacteriological Profile of Surgical Site Infection: A Descriptive Study at Deido District Hospital in Douala, Cameroon

Abstract

Background: Surgical site infection (SSI) is defined as infections occurring within 30 days after a surgical operation, or within one year if an implant is left in place after the procedure. Surgical site infection is classified by the american center for disease control (CDC) into superficial incisional surgical site infections SSI, deep incisional SSI and organ/space SSI. Objectives: The objectives of this study were to determine the prevalence of post-surgical site infections, assess the risk factors, determine the various and most microorganisms encountered and study the antibiotic sensitivity in post-surgical site infection after post-surgical site infection in Deido district hospital Douala. Materials and Methods: we conducted a 3 months hospital based prospective study on general surgery, obstetric and gynecologic records admission at the Deido district Hospital Douala from February 1st 2020 to April 30th 2020. We included available files of the general surgery, obstetrics and gynecology. We excluded paediatrics and medical. The study was approved by the institutional ethic review board of the faculty of health sciences of the university of Bamenda. Results: We had 133 of post-surgical patients in general surgery, obstetric and gynecologic. The prevalence of post-surgical site infection was 32,3% (43/133). Male gender aged 50-60 years were more affected than female to developed SSI. Diabetes mellitus and immunodepression by the human immuno deficiency virus had respective prevalence of 48.1 and 81,8% and increased hosptal stay after operation. Peritonitis with perforation was the most involved (14%). The identified germs were Staphylococcus aureus (11,3%), followed by Escherichia coli (8%), Pseudomonas aeruginosa (3,8%) and pseudomonas spp (3%). Staphylococcus aureus was sensible to vancomycin (73,33%), netilmicin, amikacin (6o%). Escherichia coli was sensible to gentamycin, ciprofloxacin, augmentin with a prevalence of 63,64%. Pseudomonas aeruginosa was sensible to pristinacine (80%) and amikacin (60%). Pseudomonas spp was sensible to netilmicin, amikacin (75%) followed by gentamicin, levofloxacin and ofloxacin (50%). Conclusion: The prevalence of Post-surgical site infection was high,  the clinical spectrum and bacterial  sensitivity was diverse.