Innovative Approaches in Glioblastoma Treatment: The Role of Optune in Enhancing Patient Survival

Abstract

Glioblastoma multiforme (GBM) is the most common form of malignant primary brain and CNS (central nervous system) tumors in adults. Prognosis is generally poor and the current standard for treatment often fails to meet expectations. In recent years, Optune has garnered attention for its novel approach to cancer treatment. Utilizing biophysical principles, Optune employs tumor-treating fields (TTFields) to preferentially disrupt cells undergoing mitosis. In this review, we examine Optune’s current role in progressing cancer treatments through its unique mechanism of action. We consider its future application with other carcinomas and current drawbacks and adoption from a biological and economic standpoint.