Species Distribution and Drug Susceptibility of Candida Isolates from Various Clinical Specimens at a Tertiary Care Hospital in Kashmir
Asifa Nazir, Farhath Kanth, Anjum Farhana
Microbiology Research Journal International · pp. 1–6 · Published 22 Mar 2016
10.9734/BMRJ/2016/24548Abstract
Aims: The aim of our study was to identify the distribution of Candida species among clinical isolates and their sensitivity pattern for common antifungal drugs. Study Design: Prospective observational study. Place and Duration of Study: Department of Microbiology, Government Medical College Srinagar, Kashmir, India, from December 2014 to January 2016. Methodology: Identification of hundred and five different Candida species as well as antifungal sensitivity testing was performed with Vitek2 Compact (Biomerieux France) using vitek 2 cards for identification of yeast and yeast like organisms (ID-YST cards). Results: Among the 105 culture positive isolates, 35 (33.3%) were C. albicans and 70 (66.6%) were Non Candida albicans (NCA). Among NCA, 35 (50%) were C. tropicalis followed by other species. All the Candida isolates were sensitive to micafungin and capsofungin whereas the susceptibility pattern of amphotericin B varied from 75.6% to 100% and the highest rates of resistance were seen for fluconazole. Conclusions: Infections caused by Candida sp are on the rise. Hence accurate identification and susceptibility pattern is necessary for management of all Candida infections.
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