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Research Article Open access CC BY 4.0

Permeable Oval Foramen and Cerebral Vascular Accident in a Young Person: A Case Study in Chad

Brahim Nassour Aware, Ali Adam Ahamat, Ousmane Mahamat Alkher, Djidda Abakar, Yahya Kichiné, Azaki Mahamat, Achta Adam Fadoul, Mbaidedjim Sylvain

Asian Journal of Cardiology Research · pp. 116–120 · Published 21 Mar 2026

10.9734/ajcr/2026/v9i1359

Abstract

Stroke is a real public health problem with a significant socio-economic impact and a high mortality risk. Its frequency in young people is between 10 and15% of all strokes. The persistence of a patent foramen ovale is one of the causes of cerebral ischaemia in young people, most commonly through paradoxical embolism. We report the case of a 17-year-old girl who presented with cerebral ischaemia with hemorrhagic transformation, revealing an 11 mm PFO with right-to-left shunting. In light of this clinical case, two hypotheses emerge: either our young girl has a right-to-left shunt responsible for cerebral ischaemia that has reached the stage of haemorrhagic infarction, or she has a cerebral haemorrhage following vascular ischaemic softening secondary to an inflammatory flare-up, which would explain why our patient had flu-like symptoms one week before her admission.

Paradoxical embolism cerebral ischaemia cerebrovascular disease serology

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