Skip to content
Research Article Open access CC BY 4.0

Evaluation of Total Protein in Malaria Parasitaemia

Roseanne Adah Ikpeama, Benjamin Nnamdi Okolonkwo, Clement Ugochukwu Nyenke, Chukwubike Udoka Okeke, Chinonye Oluchi Ezenwaka

International Journal of Pathogen Research · pp. 166–171 · Published 23 Dec 2023

10.9734/ijpr/2023/v12i6265

Abstract

Malaria endemicity is most common in the tropical region, continuous transmission still occurs in about 85 countries and regions. The liver is very essential in overall body physiology and it plays a very important role in the life cycle of malaria and its function may be altered due to malaria parasitaemia. This cross sectional study was aimed at evaluating the level of total protein in malaria parasitaemia among children attending Braithwaite Memorial Specialist Hospital, Palmars, Omega Children Hospital, Early Breed Group of Schools, St Francis Nursery and Primary school and Staff Nursery and Primary school in Port Harcourt, Rivers state Nigeria. Of the 1000 subjects within 1-10 years, 694 subjects had malaria parasitaemia while 306 subjects had no malaria and thus made up the control group. Venipuncture technique was used to collect samples for estimation of malaria parasite density and total protein (TP) using biuret method. The results showed low (873.8±30.44), moderate (3248±109.31) and high malaria (24813.8±877.22) densities with TP values of 42.70±0.50g/l, 43.21±0.60g/l and 39.64±0.60g/l respectively. There was a significant difference (P-value<0.05) in total protein (TP) levels among various groups of malaria densities. This study has shown that the impact of malaria on the liver health vary depending on the level of the infestation.

Evaluation total protein malaria parasitaemia

References (15)

  1. 1 The American Journal of Tropical Medicine and Hygiene [DOI]
  2. 2 Emergency department management of mosquito-borne illness: malaria, dengue, and West Nile virus.
  3. 3 Tietz Textbook of Clinical Chemistry [DOI]
  4. 4 Serum Protein Electrophoresis: An Underused but Very Useful Test [DOI]
  5. 5 Structural and functional integrity of human serum albumin: Analytical approaches and clinical relevance in patients with liver cirrhosis [DOI]
  6. 6 Antioxidant status and acute malaria in children in Kampala, Uganda. [DOI]
  7. 7 Liver pathology in Malawian children with fatal encephalopathy [DOI]
  8. 8 Evaluation of Malaria Parasitaemia among COVID-19 Patients in Rivers State, Nigeria [DOI]
  9. 9 Therapeutic Effects of Vitamin E on Paraquat Induced Liver Toxicity in Male Albino Rats (Rattus norvegicus) [DOI]
  10. 10 Implication of Malaria on Liver Health [DOI]
  11. 11 Activities of some liver enzymes in serum of P. falciparum malarial infected humans receiving artemisinin and non-artemisinin-based combination therapy
  12. 12 Falciparum malaria associated changes in biochemical indices in children [DOI]
  13. 13 Prevalence of Plasmodium falciparum Malaria among Children Residing in Urban and Peri-urban Settlements in Rivers State [DOI]
  14. 14 Evaluation of Liver Function Tests among Sudanese Malaria Patients [DOI]
  15. 15 Journal of pharmaceutical and biomedical analysis [DOI]

Cited by 0

No indexed citations yet.

Related research

Article metrics

Real usage data collected on this platform.

1

Page views

0

PDF downloads

0

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.