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Research Article Open access CC BY 4.0

Evaluation of Total Leucocyte Count among Menstruating Female Students Aged 16-30 at Lead City University, Ibadan

Adesina Beatrice Ebun, Oniye Adesola Helen, Amusan Festus Olatunbosun, Olufemi Olabisi Ajoke, Inegbenebor Sylvester Ehilenbalu, Akpan Richard Peter, Alabi Raphael

International Journal of Research and Reports in Hematology · pp. 24–30 · Published 4 Feb 2025

10.9734/ijr2h/2025/v8i1162

Abstract

Introduction: The menstrual cycle and other physiological processes have an impact on the total leucocyte count (TLC), a crucial indicator of immunological function. TLC and immunological regulation are known to be impacted by hormonal changes, blood loss, and physiological stress during menstruation. Aim/Objective: This study evaluated the variations in total leucocyte count among menstruating female students aged 16-30 years at Lead City University, Ibadan, Nigeria. Method: Using a hemocytometer and manual leucocyte counting, 88 people participated in a descriptive cross-sectional study. SPSS was used to gather and analyze sociodemographic data as well as information on menstrual cycle features. Results: Participants who were menstruation had a substantially lower mean leucocyte count (4.773 ± 0.8309 × 10^9/L) than those who were not (6.330 ± 0.9207 × 10^9/L). Leucocyte count was strongly impacted by age group, menstrual cycle length, and menstrual duration. Conclusion: Leucocyte counts significantly drop during menstruation as a result of immunological modulation, blood loss, and hormonal changes. This emphasizes the necessity of contextualized clinical interpretation of menstrual leucocyte numbers.

Total leucocyte count menstruation immune function hormonal fluctuations menstrual cycle

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