Evaluation of Phytochemicals and Histochemicals of Cyperus rotandus and Its Thrombolytic Activity
N. Prabhu, R. Kiruthiga, R. Kowsalya, S. Jeevitha, M. Vijay Pradhap Singh, A. Archana, T. Gajendran
Journal of Pharmaceutical Research International · pp. 18–30 · Published 9 Feb 2022
10.9734/jpri/2022/v34i8B35480Abstract
Plants are one of the most abundant sources of potentially useful chemical compounds and medicinal properties. As a result, over the last few decades, the market for plant research has been steadily increasing all over the world. The future pharmacological behaviours of Cyperus rotundus Linn. are assessed using a literature review as a basis. Extracts from various sections of the plant (aerial component, tuber, rhizomes, etc.) produce significant amounts of medicinal active compounds, as well as the chemical structures of phytochemical constituents. The aim of this analysis was to look into the thrombolytic action of Cyperus rotandus methanolic extracts. The fraction's thrombolytic effect was studied in clot lysis experiment. In a thrombolytic activity test, the extract caused 60 % lysis of the blood clot, compared to 70.10 % and 4.70 % lysis for the positive control (streptokinase) and negative control (saline water), respectively. As a result, the extract possessed significant thrombolytic activity. To determine which compounds are responsible for the current pharmacological activities, detailed pharmacological and phytochemical studies are needed. The phytochemical research revealed the presence of phytochemical constituents in various solvent fractions. The presence of these phytochemicals was found to be responsible for the plants' in-vitro thrombolytic action.
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