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Research Article Open access CC BY 4.0

Etiology and Management of Hypoventilation Syndromes

Mohammed Salah Hussein, Monera Abdulrhman Mohammed Abdulhaq, Albadi Abdullah Anwar A, Morteda Jasim Alsalim, Abdulrahman Hafidh A. Alghamdi, Montadher Mahfoudh A. Alzidany, Noor Khalid Abdulrazaq Aljarba, Alqurashi, Qays Ahmad M, Rakan fahad Alsinaideh, Tariq Fayadh Alanazi, Mohammed Mehthel Alqahtani, Abdulrhman Abdulaziz Albrkheel, Salman Fahad Alkhodairy

Journal of Pharmaceutical Research International · pp. 314–322 · Published 19 Aug 2021

10.9734/jpri/2021/v33i41A32331

Abstract

A number of diseases affecting central ventilation, breathing mechanics or both, characterize hypoventilation syndromes. The incidence of hypoventilation syndromes varies according to the underlying reason. The hypoventilation syndrome's clinical symptoms are generally vague and are in most cases due to the underlying clinical condition. More individuals develop hypercapnia and hypoxemia as hypoventilation continues to worsen. Therefore, clinical indications of hypoxemia such as cyanosis, and evidence of hypercapnia may also be present. Regardless of the etiology, successful hypoventilation therapy focuses on the underlying illness and noninvasive ventilation. Treatment for these diseases includes integrated main disorder treatment and, increasingly, non-invasive positive pressure breathing. In this paper, we overview current evidence regarding different etiologies and management of hypoventilation syndromes. Data was collected during the period of 6 months searching Pubmed, EPISCO, Web of science, Google scholar databases to include papers with relative topics.

ventilation hypoventilation positive pressure ventilation obesity congenital

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