Epidemiology of Pathogens Causing Urinary Tract Infections in Rural Communities of Enugu State, Nigeria

Abstract

Urinary tract infection (UTI) is the infection of any part of the urinary tract, and about 150 million people worldwide develop UTI each year. Its is caused by bacteria, though fungi and viruses are etiologic agents, and can occur in community and hospital settings. This study was conducted to determine the epidemiology of pathogens causing urinary tract infections in Rural Communities of Enugu State, Nigeria. A total of 735 clean catch mid-stream urine samples were collected and tested for bacteriuria from February, 2021 to June, 2021. The participants were assessed clinically to ascertain eligibility for participation, and urine samples were assessed microbiologically to isolate pathogens causing UTI. Pathogens isolated were identified morphologically, and biochemically, and results were tabulated, with respect to participants demographics. Total number of participants that participated in urine culture was 735, of this number, 172(23.40%) were males, whereas 563(76.60) were females. 510(69.39%) were married whereas 225(30.61%) were single. Total number of bacterial isolates obtained was 649 (88.30%).  Of this, Escherichia coli was the most prevalent, 316 (48.7%), followed by Staphylococci, 154 (27.7%). The least represented isolate was Pseudomonas, 2 (0.3%). Of the total number of isolates obtained, 151(23.27%) came from males, whereas 498 (76.73%) were from females. Total number of married participants with positive bacteriuria was 449 (69.18%), and those of them that were single constituted 198(30.51%). Age range of 31-40 gave the highest level of bacteriuria 151 (23.27%), followed by age range of 21-30, 146 (22.50%). The least representation of bacteriuria was seen among age group 10-20, 39(6.01%). The prevalent of UTI in this study was high, and females, youths, and married people showed a positive correlation with community acquired urinary tract infection. Intermittent screening of rural dwellers for positive bacteriuria, with emphasis paid on clinical symptoms and proper treatment will go a long way in tackling the menace of urinary tract infection in our rural communities.