Elevated β-hCG and Delayed Diagnosis of Non-Seminomatous Testicular Cancer: A Case Report Highlighting the Role of Self-Examination in Early Detection
Rodrigo Villarreal-Zavala, Elvira León-García, Carlos A. Ruiz-Larios, María Erika Gutiérrez-De la Cruz, María Valeria Jiménez-Báez
International Journal of Medical and Pharmaceutical Case Reports · pp. 37–42 · Published 4 Jul 2025
10.9734/ijmpcr/2025/v18i3433Abstract
Background: Testicular cancer, while rare, remains the most common solid malignancy among young males aged 14 to 40 years. Early diagnosis is critical for improving outcomes, yet delayed presentation is common. Case Presentation: We describe the case of a 19-year-old male presenting with hemoptysis and a long-standing painless testicular mass. Laboratory tests revealed markedly elevated β-hCG and normal AFP levels. Imaging showed pulmonary metastases and para-aortic lymphadenopathy. Radical orchiectomy confirmed a non-seminomatous germ cell tumor, and the patient began chemotherapy with etoposide and cisplatin. Conclusion: This case underscores the value of testicular self-examination and timely evaluation of testicular abnormalities. Education on self-examination is vital to promote early detection and improve prognosis in testicular cancer.
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