Efficacy of Pippali Rasayana as an Adjuvant Therapy on Pulmonary Function in Patients of Chronic Obstructive Pulmonary Disease

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) is a chronic, recurrent condition, prevalent in the general population. In modern medicine, treatment modalities are aimed to diminish the incidence and extreme aggravation of clinical features. Nowadays, pippali rasayana being considered as a promising treatment approach for COPD. However, due to methodological limitations, there is no strong evidence to support pippali rasayana.  Aim: The goal of the study is to evaluate the efficacy of Pippali Rasayana on pulmonary function in COPD patients Materials and Methods: It is double arm randomized placebo controlled single blind clinical trial. Total 60 patients of COPD will be randomly divided into two groups (each group contain 30). In both groups, standard treatment of modern medicine will be continued. With this, in Group A (Intervention), pippali rasayana 5 gm (25 gm twice a day after meal ) with honey will be given for 45 days and Group B (placebo group) will be given placebo (250 mg twice a day after meal ) with water for 45 days. Assessment will be done on 15th, 30th and 45st day. Results: Result will be declared on the basis of effect of pippali rasayana with pulmonary function test as well as frequency of Dyspnea, Chronic cough, Excessive sputum production. Conclusion: This trial may provide evidence on the efficacy of pippali rasayanaon pulmonary function in COPD.