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Effects of PAH Mixtures on Haematological, Hepatic and Oxidative Stress Biomarkers in Clarias gariepinus

Uchechukwu O. Osuagwu, Cosmas O. Ujowundu, Linus A. Nwaogu, Reginald N. Nwaoguikpe

Asian Journal of Fisheries and Aquatic Research · pp. 9–16 · Published 11 May 2023

10.9734/ajfar/2023/v22i4576

Abstract

Haematological, hepatic and oxidative stress parameters in juvenile Clarias gariepinus exposed to a combined ternary mixture of naphthalene, phenanthrene and benzo[a]pyrene were investigated under static-renewal bioassay conditions. The test organisms were exposed to two levels of treatments of the mixed compounds for a period of 35 days. Red blood cell (RBC) count, haemoglobin (Hb) concentration and haematocrit (Hct) were significantly lowered in exposed fish compared to the control. Significant decreases were also observed in mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC). White blood cell (WBC) and platelet (PLT) counts were significantly raised in exposed organisms compared to the control. There were significant reductions in total plasma protein and bilirubin. While increases in superoxide dismutase (SOD) and catalase (CAT) were significant, that of glutahthione s-tranferase (GST) was not significant.

Biomarkers naphthalene phenathrene benzo[a]pyrene haematological hepatic oxidative stress

References (11)

  1. 1 The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase [DOI]
  2. 2 Colorimetric assay of catalase [DOI]
  3. 3 Wintrobe’s Clinical Hematology [DOI]
  4. 4 Biomarkers of Oxidative Stress and Heavy Metal Levels as Indicators of Environmental Pollution in African Cat Fish (Clarias gariepinus) from Nigeria Ogun River [DOI]
  5. 5 Toxicities of Polycyclic Aromatic Hydrocarbons for Aquatic Animals [DOI]
  6. 6 Gastrointestinal uptake and fate of cadmium in rainbow trout acclimated to sublethal dietary cadmium [DOI]
  7. 7 Effects of phenanthrene on growth and basic physiological functions of the olive flounder, Paralichthys olivaceus [DOI]
  8. 8 Quantitative Determination of Lethal Concentration Lc50 of Atrazine on Biochemical Parameters; Total Protein and Serum Albumin of Freshwater Fish Grass Carp (Ctenopharyngodon idella) [DOI]
  9. 9 Dose specific responses of Anabas testudineus (Bloch) to anthracene (PAH): Haematological and biochemical manifestation [DOI]
  10. 10 Effects of diluted bitumen exposure and recovery on the seawater acclimation response of Atlantic salmon smolts [DOI]
  11. 11 USEPA United States Environmental Protection Agency [DOI]

Cited by 4

Ecotoxicological Effects of Polycyclic Aromatic Hydrocarbons in Aquatic Organisms

Thiarlen Marinho da Luz · The Handbook of Environmental Chemistry · 2024

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