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Research Article Open access CC BY 3.0

Effect of Momordica charantia (Bitter Melon) Leaves on Haemoglobin Concentration in Male Albino Rats

Adedeji G. Temitope, Ojulari S. Lekan

International Blood Research & Reviews · pp. 82–86 · Published 7 Feb 2014

10.9734/IBRR/2014/8139

Abstract

This research work was carried out to investigate the effect of the aqueous extract of Momordica charantia on haemoglobin concentration in albino rats. The aqueous extract of Momordica charantia was prepared from the leaves of the Momordica charantia plant and given orally to the experimental animals. Haemoglobin concentration was determined after two weeks of administration. The aqueous extract was prepared and given orally at doses of 80, 100, 120 and 140 mg/kg body weight daily to the experimental animals. This study was carried out at the Department of Physiology, College of Medicine, University of Ilorin between July and August 2010. The results of the work showed that there was significant decrease in mean haemoglobin concentration in test animals in comparison with the control (p<0.05). Oral administration of aqueous extract of Momordica charantia causes a decrease in haemoglobin concentration which can lead to anaemia.  

Momordica charantia haemoglobin concentration anaemia malaria

References (7)

  1. 1 Pharmacological actions and potential uses of Momordica charantia: a review [DOI]
  2. 2 The search for natural bioactive compounds through a multidisciplinary approach in Bolivia. Part II. Antimalarial activity of some plants used by Mosetene indians [DOI]
  3. 3 Antiprotozoal and cytotoxic screening of 45 plant extracts from Democratic Republic of Congo [DOI]
  4. 4 Mosquito larvicidal properties of Momordica charantia Linn (family: Cucurbitaceae).
  5. 5 In vitro antimalarial activity of six medicinal plants [DOI]
  6. 6 The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria [DOI]
  7. 7 Plants showing antiplasmodial activity--from crude extracts to isolated compounds.

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