Eclipta alba Derived Phytochemicals against Jaundice
Sutapa Mohanty, Mukesh Kumar Biswal, Sanchayita Nayak, Bhagyeswari Behera, Ushasree Mandal, Srimay Pradhan
Journal of Pharmaceutical Research International · pp. 116–119 · Published 25 May 2020
10.9734/jpri/2020/v32i730520Abstract
Phytochemicals otherwise known as secondary metabolites means the small organic molecules that are not essential for growth, development and reproduction but can protect from various diseases. Infact these phytochemicals are the key source of medicine. Secondary metabolites from Eclipta alba plant extract are traditionally used to cure Jaundice which is caused by Leptospira interrogans. The curative property of Eclipta alba against Leptospira interrogans was proved by molecular docking method in “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” recommended that pentadecan, heptadecane, 6,10,14-trimethyl-2-petadecanone can successfully deactivate the thioredoxin-disulfide reductase enzyme thereby disrupting the cellular function as well as the lifecycle of causative organism.
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