Sero-prevalence of HPV-16 IgG Antibodies and Its Association with Socio Demographic Features of Women in Lokoja, Kogi State, Nigeria

Abstract

Aim: To determine the sero-prevalence of Human Papilloma Virus type 16(HPV-16) immunoglobulin G antibodies and its association with socio-demographic features of women attending some clinics in Lokoja, Kogi State, Nigeria. Study Design: Hospital based cross sectional study. Place and Duration of Study: Kogi State specialist hospital and Federal medical Centre, Lokoja. Kogi State, Nigeria, between June and October, 2015. Methodology: We included 400 participants (380 pregnant and 20 non pregnant women; age range 15 to 45 years) attending the hospitals during the duration of the research. Serum samples were analysed for human papilloma virus type 16 IgG using the Enzyme Linked Immunosorbent Assay and questionnaire was also administered to obtain demographic features of the participants. Results: The prevalence of human papilloma virus type 16 IgG antibodies was found to be 10%. The occurrence of IgG antibodies to human papilloma virus was found to be statistically associated with educational status and occupation (P = 0.020 and 0.036 respectively). Conclusion: The prevalence of human papilloma virus was high. Cervical screening centres should be established in all areas of the state and awareness campaigns should be organized to afford young women the knowledge and dangers of cervical cancer and preventive measures.