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Research Article Open access CC BY 4.0

Distribution of Ocular Perfusion Pressure in Hypertensive Patients

S. Shruthi

Journal of Pharmaceutical Research International · pp. 189–194 · Published 29 Aug 2020

10.9734/jpri/2020/v32i2030742

Abstract

Aim: To describe the distribution of ocular perfusion pressure hypertensive patients. Design: Cross-sectional observation study. Materials and Methods: Hospital-based, case control cross-sectional study conducted on 100 patients. Systolic and diastolic blood pressure (SBP and DBP) was measured with a Mercury Sphygmomanometer. Mean ocular perfusion pressure (MOPP) = ⅔ (mean arterial pressure − IOP), where mean arterial pressure (MAP) = DBP + ⅓ (SBP − DBP), systolic perfusion pressure (SPP) = SBP – IOP and diastolic perfusion pressure (DPP) = DBP − IOP was calculated. Results: High values of diastolic BP (>90 mmHg) and low values of OPP (<40 mmHg) were associated to an increased risk of confirmed POAG. Conclusion: There is a close relationship between OPP and confirmed glaucoma in hypertensive patients.

Diastolic Perfusion Pressure (DPP) Intraocular Pressure (IOP) Ocular Perfusion Pressure (OPP) Primary Open-Angle Glaucoma (POAG).

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