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Research Article Open access CC BY 4.0

Different Areas of Carica papaya Linn Display Antifungal and Antimicrobial Activity

Ram Vighne, Gaurav Mude, Chaitali Dangore, Mona Kapse, Sudarshan Behere

Asian Journal of Research in Medical and Pharmaceutical Sciences · pp. 22–31 · Published 25 Jul 2022

10.9734/ajrimps/2022/v11i330192

Abstract

The plants of Carica papaya are utilised for nutritional and therapeutic purposes. The phytochemical examination of the leaf extract of Carica papaya reveals all phytochemical elements, including saponin, flavonoid, glycoside, alkaloid, carbohydrates, tannins, and steroids. A systematic phytochemical analysis was used to check all extracts for the presence of phytochemical components. Free radical scavenging; wound healing; neuroprotection; diuretic; abortifacient; antifertility; anti-sickling; neuroprotective; diuretic; abortifacient; Antimicrobial properties of papaya seed extracts have been shown to be effective against B. cereus, S. faecalis, S. aureus, and a variety of bacterial pathogens. Anti-inflammatory properties of an ethanolic extract of Carica papaya L. leaf were investigated in rats with paw oedema. In order to create the extract, many solvents were used such as alcohol, methanol, and ethanol as well as aqueous extracts such as acetone and chloroform. The research indicates that the latex of papaya fruits exhibits substantial efficacy against Candida albicans. The well diffusion approach inhibits S. aureus more effectively than E. coli when using methanol extract. It has antifungal, antibacterial, anti-inflammatory, antioxidant, anti-diabetic, wound-healing, and analgesic properties, among others. According to the findings of this investigation, when given in doses of 50, 75, and 100 mg/ml, Carica papaya leaf extract had more antifungal activity against Colletotrichum gloeosporioides than Fusarium spp., Rhizopus stolonifer, and antibacterial activity than aqueous papaya leaf extract.

Carica papaya latex Candida albicans

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