Design, Development and in vitro Assessment of Flurbiprofen Microemulsion Gel for Transdermal Drug Delivery
Heera Battu, Nimmathota Madhavi, K. Nithiyanand Reddy
Journal of Pharmaceutical Research International · pp. 67–76 · Published 2 Aug 2022
10.9734/jpri/2022/v34i46A36381Abstract
The aim of current research is to develop flurbiprofen microemulsion gel for transdermal delivery. To prepare a microemulsion oil, surfactant and co-surfactant selection is one of the important criteria. Selected to prepare different ratios of oil and surfactant mixture using ternary phase diagram. Based on results of physicochemical properties, we have optimized one formulation. The optimized microemulsion formulation incorporated into carbopol P 934 gel base. The In vitro diffusion of drug release shown maximum (98.6% in 12hrs) for prepared microemulsion gel than marketed gel (60.5% in 16 hrs).
Cited by 0
No indexed citations yet.
Related research
- Physical Quality of Edible Film with the Addition of Isolate Whey Protein on Water Content, Solubility, Thickness and Transparency — shares topic coverage
- Structural and Dynamic Behaviour of Heterocycles Derived from Ethylenediamines with Formaldehyde: 1,3,5-Triazinanes and Bis(imidazolidinyl)methanes — shares topic coverage
- The Effects of Spray Drying Conditions on Water Absorption Index, Water Solubility Index, Solubility and Water Activity (aw) of Rice Milk Powder — shares topic coverage
- Production and Effectiveness of Amorphous Silica Fertilizer from Rice Husks Using a Sustainable Local Energy System — shares topic coverage
- Transforming Milk Tea: Harnessing Nypa fruticans Mesocarp Flour as an Alternative for Tapioca Pearl for Sustainable Product Development and Innovation — shares topic coverage
Article metrics
Real usage data collected on this platform.
1
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.