Comparison the Effect of Paracetamol and Ketorolac on Pain Relief after Cesarean Section

Abstract

Introduction: Cesarean section is one of the most common surgical procedures in women. Effective pain control is an important component of post-operative care, as calming the mother increases her ability to take care of herself, reduce nosocomial infections, and hospitalization costs. The aim of this study was to compare the effect of paracetamol and ketorolac on the relief of post-cesarean pain in order to find a drug with minimal complications. Methods: This study was performed on 140 women admitted to Ali Ibn Abi Talib Hospital due to cesarean section. Patients were divided into two groups of 500 mg paracetamol after cord clamp and 30 mg intravenous ketorolac group. Pain score, need for additional analgesia and visual analogue scale (VAS) were measured and compared in two groups. Data were analyzed using SPSS software. Results: In this study, mean pain scores at 0, 6, 12 and 24 hours were significantly lower in the ketorolac group than in the paracetamol group. There was no complication in any of the experimental groups in this study. There was no significant difference between the mean time of first request for the additional analgesic of two groups. Frequency of additional analgesic request in the ketorolac group was significantly lower than in the paracetamol group. Conclusion: Overall, the results of this study showed that the rate of pain reduction after cesarean section with ketorolac was significantly higher than paracetamol.