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Research Article Open access CC BY 4.0

Comparison of Trace Elements Levels in Atrial Fibrillation Patients and Healthy Group

Zahra Bazargani, Manzar Banoo Shojaeifard, Gholam Abbas Valizadeh

Journal of Pharmaceutical Research International · pp. 113–119 · Published 5 Nov 2020

10.9734/jpri/2020/v32i2630846

Abstract

Background: The aim of this study is to measure the concentration of Zinc (Zn), copper (Cu)  and selenium (Se) in the blood serum of Atrial Fibrillation (AF) patients as compared to healthy subjects in both genders. Methods: This study, conducted on patients with AF (n = 50) and controls (n = 24) were evaluated by available method. Blood samples were taken from the patients and analysis of trace elements was performed by atomic absorption spectrophotometer. Statistical analyses were done using IBM-SPSS 22.0. Results: Zn and Se concentrations were evaluated in AF patients and healthy group. Zn and Se concentration in AF patients is much lower than in healthy group (p<0.008, p<0.000). AF patients showed a significantly higher Cu concentration than the healthy group (p<0.000). The data of the present study revealed that the concentrations of all trace elements had a significant difference in the serum of AF patients with respect to the healthy group (p<0.05). Conclusion: We found that concentrations of Zn & Se levels were significantly decrease in the in the serum samples of AF patients compared with the controls group.

Atrial Fibrillation trace elements zinc copper selenium.

Cited by 5

Relationship between trace elements status and atrial fibrillation in patients with valvular heart diseases

Xiang Liu, Yijia Shao, Zirui Huang · Frontiers in Cardiovascular Medicine · 2025

Role of Trace Elements in Heart Failure

Vedant Lekurwale, Tileshkumar Turankar, Sourya Acharya · Journal of Pharmaceutical Research International · 2021

Selenium as a Modulator of Redox Reactions in the Prevention and Treatment of Cardiovascular Diseases

Klaudia Leszto, Laura Biskup, Klaudia Korona · Antioxidants · 2024

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