Skip to content
Research Article Open access CC BY 4.0

Comparison of Blood Cells Parameters and Complete Blood Count in Diabetic Patients: A Cross-sectional Study

Majid Foroutan, Mohammad Nassaji, Fatemeh Oruji

Journal of Advances in Medical and Pharmaceutical Sciences · pp. 1–9 · Published 15 Nov 2022

10.9734/jamps/2022/v24i10579

Abstract

Background and Aim: Diabetes is a type of metabolic disorder characterized by increased blood glucose, which is due to insulin resistance, insulin deficiency, or both. Changes in blood cell parameters in diabetes are controversial. The present study aimed to assess the blood cell parameters in diabetic patients compared to healthy individuals. Methods: This cross-sectional study was performed on 540 cases (270 diabetic patients and 270 healthy individuals) over 20 years old who were referred to the clinics affiliated to Semnan University of Medical Sciences, Semnan, Iran, in 2018. The complete blood count (CBC) parameters were assessed in both groups, and demographic information was also collected via questionnaires. All the analyses were performed in SPSS software (version 22). Results: In terms of gender, the majority of participants (61.2%) were female. The white blood cell (WBC) count in diabetic patients was significantly higher than that in the control group (P<0.001), and the hemoglobin (HGB) level was significantly lower in diabetic patients (P=0.009). There was no significant difference in the level of other indices between diabetic and control groups. There was a significant difference between the gender of diabetic patients in HGB, red blood cell (RBC) count, and platelets (PLT) (P<0.001). Moreover, HBG and RBC were less in patients with longer diabetes duration (P<0.001). Conclusion: The obtained results pointed to a statistically significant difference in some hematological parameters of diabetic patients compared to non-diabetic individuals. More studies are needed to clarify the causal relationship between diabetes and these indices.

Blood cells parameters diabetes Red Blood Cell (RBC) White Blood Cell (WBC)

References (37)

  1. 1 Inflammation in obesity, diabetes, and related disorders [DOI]
  2. 2 Social Determinants of Health and Diabetes: A Scientific Review [DOI]
  3. 3 Oxidative stress and inflammatory markers in prediabetes and diabetes. [DOI]
  4. 4 Periodontal Disease: A Risk Factor for Diabetes and Cardiovascular Disease [DOI]
  5. 5 From Pre-Diabetes to Diabetes: Diagnosis, Treatments and Translational Research [DOI]
  6. 6 Hyperglycemia-induced oxidative stress in diabetic complications [DOI]
  7. 7 Testosterone treatment to prevent or revert type 2 diabetes in men enrolled in a lifestyle programme (T4DM): a randomised, double-blind, placebo-controlled, 2-year, phase 3b trial [DOI]
  8. 8 Vascular endothelial dysfunction, a major mediator in diabetic cardiomyopathy [DOI]
  9. 9 Mean Platelet Volume in Type 2 Diabetes Mellitus [DOI]
  10. 10 Risk and management of pre-diabetes [DOI]
  11. 11 White Blood Cells Count and Incidence of Type 2 Diabetes in Young Men [DOI]
  12. 12 Association of hematological indicies with diabetes, impaired glucose regulation and microvascular complications of diabetes.
  13. 13 Neutrophils Actively Contribute to Obesity-Associated Inflammation and Pathological Complications [DOI]
  14. 14 Platelet volume indices as predictive biomarkers for diabetic complications in Type 2 diabetic patients [DOI]
  15. 15 Hematological indices and their correlation with fasting blood glucose level and anthropometric measurements in type 2 diabetes mellitus patients in Gondar, Northwest Ethiopia [DOI]
  16. 16 Effect of diabetes self-management education (DSME) on glycated hemoglobin (HbA1c) level among patients with T2DM: Systematic review and meta-analysis of randomized controlled trials [DOI]
  17. 17 Markers of Chronic Inflammation in Overweight and Obese Individuals and the Role of Gender: A Cross-Sectional Study of a Large Cohort [DOI]
  18. 18 Phenotypic Characterization of Insulin-Resistant and Insulin-Sensitive Obesity [DOI]
  19. 19 Relationship between hematological parameters and glycemic control in type 2 diabetes mellitus patients [DOI]
  20. 20 The role of sex hormone-binding globulin (SHBG), testosterone, and other sex steroids, on the development of type 2 diabetes in a cohort of community-dwelling middle-aged to elderly men [DOI]
  21. 21 Platelet Indices as a Predictor of Microvascular Complications in Type 2 Diabetes [DOI]
  22. 22 Oxidative stress and inflammatory markers in type 2 diabetic patients [DOI]
  23. 23 White blood cells count as an indicator to identify whether obesity leads to increased risk of type 2 diabetes [DOI]
  24. 24 Can hematological parameters in type 2 diabetes predict microvascular complication development? [DOI]
  25. 25 Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey [DOI]
  26. 26 Utility of Red Cell Distribution Width (RDW) as a Noninvasive Biomarker for the Diagnosis of Acute Appendicitis: A Systematic Review and Meta-Analysis of 5222 Cases [DOI]
  27. 27 Red Blood Cell Parameters and Their Correlation with Renal Function Tests Among Diabetes Mellitus Patients: A Comparative Cross-Sectional Study [DOI]
  28. 28 Predictive value of inflammatory and hematological data in diabetic and non-diabetic retinopathy. [DOI]
  29. 29 Impact of Diabetes Mellitus on Human Erythrocytes: Atomic Force Microscopy and Spectral Investigations [DOI]
  30. 30 Effects of combined inositol hexakisphosphate and inositol supplement on antioxidant activity and metabolic enzymes in the liver of streptozotocin-induced type 2 diabetic rats [DOI]
  31. 31 The relationship between red blood cell distribution width and blood pressure abnormal dipping in patients with essential hypertension: a cross-sectional study [DOI]
  32. 32 Hematological profile associated with type 2 diabetes mellitus [DOI]
  33. 33 Association of hematological indices with prediabetes: A cross-sectional study [DOI]
  34. 34 Study of relationship between WBC count and Diabetic complications [DOI]
  35. 35 A COMPARATIVE ANALYSIS OF BIOCHEMICAL AND HEMATOLOGICAL PARAMETERS IN DIABETIC AND NON-DIABETIC ADULTS
  36. 36 Difference of Red Blood Cell Count (RBC) Levels in Diabetes Mellitus Type II with Ulcers and without Ulcers [DOI]
  37. 37 A window of opportunity against diabetes: frequency of microvascular and macrovascular complications in prediabetes [DOI]

Cited by 5

Alterations in Whole Blood Count Parameters and Some Inflammatory Biomarkers of Occupationally Exposed Metal Recyclers: A Case-Control Study

Lydia Amarachi Onwuemelem, Akpourhievwe Ogbor, Haruna Mallah Ayuba, Daniel Oyedemi, Efosa Frances Osunde, Alufokhai Ohijei, Daniel Ebubechi Obasi, Jikmyan Jactu Sunday, Irene Adjoa Anderson, Afolabi Martins Oladega · Asian Hematology Research Journal · 2025

Showing 2 of 5 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

35

Page views

0

PDF downloads

2

Outbound clicks

5

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.