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Research Article Open access CC BY 4.0

Co-Relation of Steriods in Diabetic and COVID-19 Patients

James Lalduhawma, Kumar Gaurav Chhabra, Amit Reche, Priyanka Paul Madhu, . Lalruatzela, Jonathan Lalnunsanga

Journal of Pharmaceutical Research International · pp. 128–135 · Published 19 Oct 2021

10.9734/jpri/2021/v33i46B32924

Abstract

An unusual rise in blood glucose linked with the use of glucocorticoids in a patient with or without a prior history of diabetes mellitus is referred to as steroid-induced diabetes mellitus. The term steroid refers to a group of chemicals that have varied physiological effects. Hydrocortisone are a class of hormones that comprises both lab-made and naturally occurring hormones. Steroids are naturally occurring hormones in the human body. Corticosteroids have a wide spectrum of effects, from solely glucocorticoid to solely mineralocorticoid, and steroid compounds are chosen based on their suitability for a particular therapy. A drug may have anti-inflammatory resources, it could also have mineralocorticoid action, which lowers blood pressure. Steroids are drugs that have been used extensively in a variety of conditions. Glucocorticoids, despite being frequently recommended for their anti-inflammatory and immunosuppressive characteristics, have a number of side effects, with hyperglycemia being one of the most common and representative. In diabetic individuals, corticosteroids are generally contraindicated due to the danger of altering glucose control and resulting in severe decompensation. However, if given early and in a well-controlled regimen, corticosteroid medication can be useful in some patients. With good knowledge of the pharmacokinetics of the glucocorticoid utilized, glucose disequilibrium after withdrawal can be predicted.

DIABETIC blood glucose public health glucocorticoids

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