Isoniazid Derived Schiff Base Metal Complexes: Synthesis, Characterization, Thermal Stability, Antibacterial and Antioxidant Activity Study
Farzana Khanm Camellia, Md. Ashrafuzzaman, Md. Nazrul Islam, Laila Arjuman Banu, Md. Kudrat-E- Zahan
Asian Journal of Chemical Sciences · pp. 23–36 · Published 14 Jun 2022
10.9734/ajocs/2022/v11i419131Abstract
Transition metal complexes of Cu2+, Ni2+ and Co2+ with the Schiff base ligand, N-(2-methoxybenzylidene)isonicotinohydrazone, (L1) were synthesized by the conventional condensation approach. Ligand and its metal were characterized by FT-IR, UV-Vis, Magnetic moment measurements and Thermogravimetric (TGA) analysis. IR spectra revealed that the Schiff base ligand coordinated to the metal ion through nitrogen (N) of azomethine group and oxygen (O) of carbonyl group. IR data coupled with TGA analysis confirmed the presence of coordinated water molecules. Antibacterial activity for both ligand and its complexes were investigated against some pathogenic bacteria and the best activity was observed in the case of the CuL1 against E. coli when compared with standard drug, Kanamycin-30. The antioxidant activity of the CuL1 complex was the greatest among all the complexes when compared to that of BHT.
Cited by 7
Yasmin Mos'ad Jamil, Fathi Mohammed Al-Azab, Nedhal Abdulmawla Al-Selwi · Ecletica Quimica · 2023
Dheya A. Hameed, Nedhal A. A. Al-Selwi, Fathi M. Al-Azab · Biointerface Research in Applied Chemistry · 2025
Md. Ali Asraf, Md. Ashraful Islam, Faria Tasnim · 2024
Yasser Fakri Mustafa · Russian Journal of Bioorganic Chemistry · 2025
Md. Ashraful Islam, Faria Tasnim, Md. Sajib Hossain · Journal of Molecular Structure · 2025
Pooja Meena, Priyanka Surya, Ved Prakash Meena · 2025
Pooja Meena, Priyanka Surya, Ved Prakash Meena · 2025
Related research
- In vitro Antioxidant and Anticancer Activity of Cyanobacteria — shares topic coverage
- Review: Parkia speciosa as Valuable, Miracle of Nature — shares topic coverage
- A Selective Review of Lipid Autoxidation and Rancidity, Antioxidants, and Dithiooxamide — shares topic coverage
- Antioxidant and Haemato-Biochemical Enhancing Properties of Daucus carota in Male Wistar Rats Toxicated with Lead Chloride — shares topic coverage
- Radical Scavenging Capacity and Efficacy of Myristica fragrans (Nutmeg) Metabolites on Cladosporum herbarum of Food Origin — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
7
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.