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Research Article Open access CC BY 4.0

Impact of Environmental Carcinogens on Africa: A Quick Review of Health Indices in Africa between 2010 and 2024

Faridah Mobolanle Banwo, Junior Josephson Chukwuma, Ewaoluwa Promise Owoyemi, Paul Agwaza Kernen, Kosisochukwu Doris Ogbonna, Eberechukwu Osinachi Azubuike, Jane-Frances Chinenye Ojobor, David Odanibeh, Chibuzo Valentine Nwokafor

Asian Journal of Biology · pp. 49–63 · Published 16 Oct 2024

10.9734/ajob/2024/v20i11448

Abstract

Cancer is a leading cause of death globally, with Africa experiencing a significant rise in cases over the past decade. This review explores the impact of environmental carcinogens on Africa's health indices from 2010 to 2024. Environmental carcinogens, comprising chemical, physical, and biological agents, contribute significantly to DNA damage, leading to cancer. These carcinogens can act directly, such as UV radiation, or indirectly, like polycyclic aromatic hydrocarbons, which require bioactivation to become harmful. Carcinogens are classified based on their mode of action and their interplay between internal factors (e.g., inherited mutations) and external factors (e.g., chemical exposure) in cancer development. This review reveals a troubling increase in cancer cases across Africa, tied to widespread exposure to carcinogens. This paper calls for urgent public health measures and policies to reduce carcinogen exposure and mitigate cancer's growing impact in Africa.

Africa cancer DNA damage environmental carcinogens

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