Assessing the Relationship between Hair and Blood Levels of Urea, Creatinine and Uric Acid: A Cross-sectional Study

Abstract

Aim: To assess the correlation between blood and hair in Urea, Creatinine and Uric Acid. Study Design: Cross-sectional study. Place and Duration of Study: Otuoke community in Ogbia Local Government Area and Eni-yimini Laboratories LTD, Yenezue-gene, Yenagoa, Bayelsa State, between June and October 2023. Methodology: A total number of fifty (50) samples were used in this research. The samples were divided into twenty-five different human hairs and twenty-five human blood samples (Araoye method). Blood samples were collected with 5ml syringe into plain tubes, the blood samples coagulated, and each of the blood samples were spun in a centrifuge at 4000rpm and the supernatant separated from the red blood cells for further analysis. Data were analyzed using one-way Anova with statistical significance considered as P < 0.05 Results: The results showed no significant correlation between urea, creatinine and uric acid concentrations. However, there was a significant difference in creatinine and uric concentration (p<0.001), when compared using ANOVA. The study suggests that hair analysis can help identify nutritional deficiencies in the body, potentially causing health problems. Although hair analysis is not as accurate as blood analysis, it can be a helpful tool for identifying problems and monitoring treatment results. Conclusion: With more research, hair analysis may rank among the best for clinical analysis in the absence of hair.