Aripiprazole Induced Hypersexuality in A 42-Year-Old Woman with Bipolar Disorder: A Rare Case Report
Hafiz Olatunde, Tajudeen Basiru, Odiaka Mark Anombem, Adeniyi Kayode Busari, Gibson Anugwom, Sochima Ochije, Salisu Aikoye
Journal of Advances in Medicine and Medical Research · pp. 218–221 · Published 31 Aug 2023
10.9734/jammr/2023/v35i205192Abstract
Background: Aripiprazole use is associated with a very rare side effect of hypersexuality, which was experienced by the patient described in this case study. Hypersexuality can be a very distressing symptom and may also hinder medication compliance. Case Presentation: A 42-year-old woman with bipolar II disorder developed hypersexuality three weeks after starting aripiprazole, which was used in the treatment of her bipolar disorder. Discussion: Aripiprazole works by reducing dopaminergic neurotransmission in the mesolimbic pathway. It is believed that due to aripiprazole’s agonistic dopaminergic action in the mesolimbic circuit, it can increase sexual desire. Conclusion: This case report emphasizes the importance of closely monitoring patients taking aripiprazole for hypersexuality and adds to the existing body of knowledge of aripiprazole-induced hypersexuality.
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