Paraneoplastic Dermatomyositis with Neurogenic Atrophy Revealing Occult Breast Carcinoma: A Case Report
Tounsi Haifa, Bouzouaya Hela, Abida Houssem, Sbai Ahmed, Ben Bahri Mariem, Mami Haifa, Farhat Emna, Mohamed Ali Sbai, Maaroufi Raja
Asian Journal of Medical Principles and Clinical Practice · pp. 645–649 · Published 6 Sep 2025
10.9734/ajmpcp/2025/v8i2324Abstract
Neuromyositis (NM) is a rare and controversial entity. We report the case of a 54-year-old female with no previous pathological history who presented with proximal myalgia. Clinical examination was remarkable for obesity, proximal muscle weakness and left axillary adenopathy. Creatine phosphokinase and lactate dehydrogenase were in the normal range. Anti-nuclear antibodies were positive with anti-Ku positive. Electromyogram was myogenic while biopsy showed DM features with neurogenic atrophy. Investigations revealed breast carcinoma associated with NM. Oral corticosteroid therapy was initiated. A left mastectomy with lymph node dissection followed by chemotherapy then adjuvant radiotherapy was carried out. Progressive improvement was obtained. The identification and collection of cases of NM is useful to improve our knowledge about this rare condition.
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