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Research Article Open access CC BY 4.0

Antioxidant, Cytotoxic and larvicidal Potential in Oxalis latifolia Kunth. Methanolic Leaf Extract

R. Gopi Krishnan, S. Murugesh

Journal of Pharmaceutical Research International · pp. 269–275 · Published 14 Oct 2021

10.9734/jpri/2021/v33i46A32866

Abstract

Aims: The current work was analyzed in antioxidants, cytotoxicity and larvicidal potential were examined for O. latifolia methanolic leaf extract. Methodology: Antioxidant assasy for Hydroxyl radical (H2O2). Cytotoxicity potential was studied against colon (HT-29). Culex quinquefasciatus  (IVth instar) larvae was used for larvicidal test. Results: Antioxidant and cytotoxicity exhibits significant activities with IC50 value of 442.94 µg/mL and also the cytotoxicity activity IC50 values of 50.00μg/mL for HT-29. Larval mortality against the larvae of Cx. quinquefasciatus showed best activity with LC50 09.50mg/L and LC90 28.72 mg/L. Conclusion: Thus, this study proved that methanolic leaf extracts of O. latifolia have significant biological activities. Hence, it can be used for pharmacetutical applications.

Larvicidal potential.HT-29 Cx. quinquefasciatus H2O2

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