Skip to content
Research Article Open access CC BY 4.0

Antioxidant and Antimicrobial Activity of Psidium guajava (Pomifera and Pyrifera) Aqueous Leaf Extract Varieties’

Grace Gakii Keddy, Patrick Gachoki Kareru, Sammy Indire Wanakai, Mercy Wanjuki Karenju, George Kiprono Kisoi, Peter Lemei Njenga

Advances in Research · pp. 124–137 · Published 30 Jun 2023

10.9734/air/2023/v24i5964

Abstract

Aims: Psidium guajava (Pomifera (red) and Pyrifera (white)) is commonly used in traditional medicine to treat gastrointestinal disorders. In this study, the antioxidant and antimicrobial activity of methanol extracts of P. guajava (Pomifera (Red) and Pyrifera (White) leave varieties were investigated. Methodology:  The total phenolic (TPC) and flavonoid (TFC) contents and antioxidant capacities in terms of 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging, were determined, and the correlations among the results were assessed. The antimicrobial activity was assessed through agar disc diffusion assays. Results: Phytochemical screening showed that the extracts had alkaloids, glycosides, saponins, triterpenoids, phenols, and flavonoids in different abundances. The aerial part- (Pomifera (red) and Pyrifera (white)) extract contained 106.502.97 and 122.072.73 mg/g in QAE phenolic content, 2650.6527.48 and 2486.829.10 mg/g in RE of flavonoids, 17.860.19 and 10.160.07 mg/g in TAE of Tannins, 69.500.14 and 10.500.01 alkaloid content, and 7.25.500.11 and 17.750.09 saponin content and displayed significant antioxidant capacity in the DPPH (IC50 = 52.17 ± 7.30 μg/mL) assay. By contrast, the P. guajava Pyrifera (white) extract contained high amounts of TPC (87.72 ± 7.75 mg GAE/g) and TFC (25.60 ± 1.57 mg QE/g). The leaf extract showed the highest inhibitory activity against highest activity was observed against E. Coli, S.E, and S. aureus (14, 15, and 16) respectively. GC-MS revealed presence of Sesquiterpenes, terpenes, and triterpenes. The leaves also contain vitamins of measurable amounts. Generally, the extracts evaluated showed potent antifungal activity against selected bacterial strains. Conclusion: The results showed that P. guajava (Pomifera (red) and Pyrifera (white)) possesses different phytochemicals displaying significant antioxidant and antimicrobial activities, thus lending credence to its use in traditional medicine.

GC-MS Psidium guajava total phenols antioxidant activity Staphylococcus aureus antimicrobial activity

References (13)

  1. 1 Determination of total phenolic and flavonoid content, antimicrobial and antioxidant activity of a root extract of Arisaema jacquemontii Blume [DOI]
  2. 2 Green synthesis of titanium dioxide nanoparticles using Psidium guajava extract and its antibacterial and antioxidant properties [DOI]
  3. 3 Green Synthesized Ag Nanoparticles for Bio-Sensing and Photocatalytic Applications [DOI]
  4. 4 Antimicrobial Activity ofSolanum aculeastrum. [DOI]
  5. 5 Flavonoids, phenolic content, and antioxidant activity of propolis from various areas of Guanajuato, Mexico [DOI]
  6. 6 Biosynthesis of iron nanoparticles using Ageratum conyzoides extracts, their antimicrobial and photocatalytic activity [DOI]
  7. 7 Phytochemical analysis of the methanol leaves extract of Paullinia pinnata linn [DOI]
  8. 8 GC and GC/MS Analysis of Essential Oil Composition of the Endemic Soqotraen Leucas virgata Balf.f. and Its Antimicrobial and Antioxidant Activities [DOI]
  9. 9 Medicinal and nutritional qualities of Zingiber officinale [DOI]
  10. 10 Functionalization of Agave Cellulose Nanoparticles and its Characterization by Microscopy and Spectroscopy Techniques [DOI]
  11. 11 Antioxidant activity and antimicrobial properties of Entada leptostachya and Prosopis juliflora extracts [DOI]
  12. 12 Evaluation of nutritional value ofAsystasia mysorensisandSesamum angustifoliaand their potential contribution to human health [DOI]
  13. 13 Qualitative and Quantitave Evaluation of the Phytochemicals in Dry, Wet and Oil Extracts of the Leaf of Morinda lucida

Cited by 3

RETRACTED: Phytochemical and GC-MS analysis of Thevetia peruviana fruit methanol extract as an anti-rodenticide potential against balb C rats

Anthony Irungu Ndung'u, Joseph Mungai Keriko, Patrick Gachoki Kareru · Heliyon · 2024

Showing 1 of 3 known citations — external sources report more than can currently be individually listed.

Related research

Article metrics

Real usage data collected on this platform.

73

Page views

0

PDF downloads

45

Outbound clicks

3

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.