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Research Article Open access CC BY 4.0

Antimicrobial Profiling of Resistant Genes in Bacteria Isolated from Drinking Water Sources in Bonny Island, Rivers State, Nigeria

Inyingierefagha Moses Wilcox, Sokari, T. G., Akani, N. P., Amadi, L. O.

Journal of Advances in Microbiology · pp. 146–157 · Published 26 Oct 2023

10.9734/jamb/2023/v23i10766

Abstract

The global health crisis of antimicrobial resistance (AMR) necessitates a profound understanding of its dynamics, particularly in environmental reservoirs such as drinking water sources. The aim of the study was to identify the presence and variety of antibiotic-resistant genes (ARGs) within bacteria isolated from drinking water sources in Bonny Island, Rivers State, Nigeria – an area characterized by unique ecological and human-induced factors. Eighty water samples were collected from drinking water distribution systems within Bonny Island for a period of six month. Bacteria isolated from drinking water samples within Bonny Island underwent antimicrobial profiling, including susceptibility tests against a range of clinically relevant antibiotics. Molecular techniques were employed to identify the isolated bacteria and characterize specific ARGs, illuminating the genetic basis of resistance in the isolated bacteria. The bacterial isolates displayed varying resistance patterns, with the highest resistance observed against cefuroxime (59.6%), cefotaxime (48.9%), ceftazidime (44.7%), ceftriaxone (36.3%), chloramphenicol, and Augmentin (29.8%), while resistance to cotrimoxazole and gentamicin was lower (12.8%). Among the bacterial isolates, the tet gene, conferring resistance to tetracycline antibiotics, was present in 46.7% of cases, while 100% exhibited the oxa gene and 93.3% possessed the aac(6’)-ib gene. Preliminary findings revealed a diverse array of bacteria with varying resistance profiles, including both common and emerging pathogens. The identified ARGs covered genes providing resistance to a broad spectrum of antibiotics, including beta-lactams, fluoroquinolones, and tetracyclines. These results underscore the potential risks associated with the spread of ARGs in drinking water sources and their potential transfer to pathogenic bacteria.

Bonny island drinking water antibiotics antibiotic resistant genes

References (17)

  1. 1 Antibiotic Resistance Genes as Emerging Contaminants: Studies in Northern Colorado [DOI]
  2. 2 Biochemical Tests for Identification of Medical Bacteria [DOI]
  3. 3 CLSI Methods Development and Standardization Working Group Best Practices for Evaluation of Antimicrobial Susceptibility Tests [DOI]
  4. 4 Prevalence of Antibiotic Resistance in Drinking Water Treatment and Distribution Systems [DOI]
  5. 5 Origin and Evolution of Antibiotic Resistance: The Common Mechanisms of Emergence and Spread in Water Bodies [DOI]
  6. 6 International Journal of Environmental Health Research 2,84-88 (1992)
  7. 7 Impact of Water Chemistry, Pipe Material and Stagnation on the Building Plumbing Microbiome [DOI]
  8. 8 New insights into antibiotic resistome in drinking water and management perspectives: A metagenomic based study of small-sized microbes [DOI]
  9. 9 Fate of antibiotics, antibiotic-resistant bacteria, and cell-free antibiotic-resistant genes in full-scale membrane bioreactor wastewater treatment plants [DOI]
  10. 10 Impact of biofilm formation and detachment on the transmission of bacterial antibiotic resistance in drinking water distribution systems [DOI]
  11. 11 Inactivation of fungal spores in water using ozone: Kinetics, influencing factors and mechanisms [DOI]
  12. 12 Positive effects of COVID-19 control measures on influenza prevention [DOI]
  13. 13 Trend Of Water Quality Status In Kelantan River Downstream, Peninsular Malaysia [DOI]
  14. 14 Toward Standards in Clinical Microbiota Studies: Comparison of Three DNA Extraction Methods and Two Bioinformatic Pipelines [DOI]
  15. 15 Beta-lactam combination therapy for the treatment of Staphylococcus aureus and Enterococcus species bacteremia: A summary and appraisal of the evidence [DOI]
  16. 16 Diversity of Multidrug-Resistant Bacteria in an Urbanized River: A Case Study of the Potential Risks from Combined Sewage Overflows [DOI]
  17. 17 Microbiological Assessment of Rainwater and Air Quality of Some Areas in Port Harcourt [DOI]

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