Antifungal Properties and Chemical Analysis of Essential Oil from Vitex negundo Seeds
Hong-Wei Ai, Yue-Xin Kang, Yang Cao, Cheng-Jian Zheng
Journal of Pharmaceutical Research International · pp. 541–548 · Published 3 Jan 2014
10.9734/BJPR/2014/7079Abstract
Aims: To investigate the constituents and antimicrobial activity of essential oil from Vitex negundo seeds. Study Design: The essential oil of Vitex negundo seeds was prepared by hydrodistillation. GC/MS technique was used to determine the volatile constituents in the oil. A total of 13 isolates of bacteria and fungi were employed to evaluate the antimicrobial activity of the oil. Place and Duration of Study: Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, between April 2010 and September 2010. Methodology: Essential oil from Vitex negundo seeds were obtained by hydrodistillation, with constituents analyzed by GC-MS. Antimicrobial activity of the oil was evaluated against both Gram-positive and Gram-negative bacteria and fungi. Results: A total of forty-two components, representing 91.36% of the oil, were identified. n-Hexadecanoic acid (17.68%), eudesm-4(14)-en-11-ol (12.39%) and caryophyllene oxide (10.79%) were found to be the major constituents. The essential oil exhibited significant antifungal activity against Candida albicans at MIC 4.0 μg/ml. Conclusion: The essential oil of Vitex negundo seeds showed potential antifungal activity and can be of potential use in pharmaceutical fields.
Cited by 14
Hadia Bibi, Niaz Ali, Muhammad Nabi · Main Group Chemistry · 2021
Diksha Sharma, Radha, Manoj Kumar · Chemistry & Biodiversity · 2023
Hazeena M Ameen, A S Athira, Ayona Jayadev · 2024
Aparna H Gopalkrishna, Seshagiri M, Sunil Muddaiah · Journal of Dental Research, Dental Clinics, Dental Prospects · 2016
Mohammad Moghaddam, Leila Mehdizadeh · Recent Trends in Antifungal Agents and Antifungal Therapy · 2016
Sylvere Landry Lontsi Dida, William Norbert Tueguem Kuate, Patrice Zemko Ngatsi · Indian Phytopathology · 2024
Mahyar Dadbin, Mohammad Soltanpour, Laleh Khodaie · Journal of Research in Pharmacy · 2025
Said Behiry, Rokaia Nabil, Hosny Younes · Scientific Reports · 2025
Sundararajan Balasubramani, Thamaraiselvi Rajendhiran, Anil Kumar Moola · Environmental Science and Pollution Research · 2017
Ahmed Abdelkhalek, Lóránt Király, Al-Naji A. Al-Mansori · Plants · 2022
Related research
- Naturally Available Essential Oils for Aromatherapy — shares topic coverage
- In vitro Screening of Antibacterial and Antioxidant Activities of Essential Oils from Four Moroccan Medicinal Plants — shares topic coverage
- Anti-Shiga Toxin Producing Escherichia coli O157:H7 Effect of Ocimum basilicum L. Essential Oil Analyzed Using Time Kill Assay in a Batch Culture — shares topic coverage
- Volatile Components and Antibacterial Profile of Essential Oils Extracted from Leaves and Twigs of Pistacia lentiscus L. — shares topic coverage
- Antibacterial Effects of Oregano Essential Oil (OEO) and Its Potential Applications — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
14
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.