Antibiotic Susceptibility Profile of Uropathogenic Enterobacteria Isolated in the Bacteriology-Virology Laboratory of the CHNU of FANN During the Year 2022

Abstract

This was a retrospective study of urine cytobacteriological examinations (ECBU) aimed at determining the antibiotic sensitivity profile of enterobacteria isolated in urinary tract infections at the bacteriology and virology laboratory of the Fann National University Hospital during the period 2022. The antibiogram was carried out by the diffusion method in agar medium according to the recommendations of the Antibiogram Committee of the French Society of Microbiology CA-SFM 2022 and patient data were extracted from the laboratory register, entered into Excel and analyzed with SPSS IBM 25 software. The prevalence of UTIs was 23.7%, enterobacteria represented 70.32% of the isolated germs with a predominance of E. coli (48.5%) followed by K. pneumonia (23.7%) and Enterobacter spp. (11. 6%). It is noted poor susceptibility of the strains to beta-lactams, with extended spectrum Beta-Lactamase rates of 46% for E. coli, 53.5% for K. pneumoniae, and 50% for Enterobacter spp. ESBL-Es had good susceptibility to imipenem and amikacin (91.9% and 83.7%), respectively. However, poor activity was noted with floroquinolones, with resistance rates of 66.7% for ciprofloxacin and 62% for norfloxacin.