Skip to content
Research Article Open access CC BY 4.0

Antibacterial Properties of Boerhavia diffusa and Huntaria umbellata on Bacteria Isolated from Blood Samples of Malaria Patients.

Omoya, O. F., Onifade, A. K., Ologun, O. M.

Journal of Advances in Microbiology · pp. 51–64 · Published 18 Apr 2024

10.9734/jamb/2024/v24i4815

Abstract

Malaria remains a major infectious disease ravaging the tropical part of the world with more deleterious effects on tropical low- and middle-income nations. Aside from the complications, secondary infections by bacteria have become rampant; hence, the need for the antibacterial properties of Boerhaavia diffusa and Huntaria umbellate extracts. Bioactive ingredients of the plants were extracted using standard methods and the extracts were subjected to filtration using a membrane-injection filter. Malaria positive blood samples were obtained and the bacteria present in them were isolated and identified before subjecting them to sensitivity test on the extracts. The results showed that steroids and tannin were not detected in both cold and hot water extracts while glycoside was the most abundant in the extracts, followed by terpenoid and phenol. The probable bacteria generally identified are Acinetobacter, Escherichia, Klebsiella, Staphylococcus, Salmonella, Streptococcus and Pseudomonas. The bacteria with the highest frequency of occurrence were Salmonella and Staphylococcus. The least occurred bacteria was Pseudomonas. Both Staphylococcus and Salmonella had 28% of occurrence in all the samples. Salmonella was most susceptible to ampicillin having a diameter of zone of inhibition of 18.33±0.58 mm, while it was not susceptible at all to nitrofurantoin. Escherichia was most susceptible to tetracycline with a zone diameter of 14.33±0.58 mm, while Pseudomonas was most susceptible to ampicillin having a zone diameter of 10.00±0.00 mm. At 100mg/mL concentration, the highest diameter of zone of inhibition was 11.33±0.58. The results obtained in this study have shown that both B. diffusa and H. umbellate extracts have a high antibacterial effect.

Antibacterial extracts malaria isolates

References (7)

  1. 1 The cochrane database of systematic reviews [DOI]
  2. 2 Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology [DOI]
  3. 3 Anthocyanins, Flavonols, and Free Radical Scavenging Activity of Chinese Bayberry ( Myrica rubra ) Extracts and Their Color Properties and Stability [DOI]
  4. 4 Fine-scale spatial distribution of deltamethrin resistance and population structure of Anopheles funestus and Anopheles arabiensis populations in Southern Mozambique [DOI]
  5. 5 Evaluation and lead optimization of anti-malarial acridones [DOI]
  6. 6 Care-seeking behaviour and socio-economic burden associated with uncomplicated malaria in the Democratic Republic of Congo [DOI]
  7. 7 Phytochemical components of Hunteria umbellata (K. Schum) and its effect on isolated non-pregnant rat uterus in oestrus.

Cited by 0

No indexed citations yet.

Related research

Article metrics

Real usage data collected on this platform.

5

Page views

0

PDF downloads

0

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.