Anti-inflammatory Potentials of Fibraurea tinctoria Leaves Extract in Experimental Rats or Animals
Journal of Pharmaceutical Research International · pp. 79–83 · Published 3 Jun 2020
10.9734/jpri/2020/v32i830474Abstract
The activity of the hydroalcoholic extract of Fibraurea tinctoria leaves and anti-inflammatory was investigated. We utilized rats for which oedema was induced by carrageenan. The extract of Fibraurea tinctoria leaves was administered orally at doses of 100, 200 and 400 mg/kg. Paw oedema was significantly minimized using all prepared doses of the extract administered. The 400 mg/kg dose producing the highest oedema reduction. The Percent Inhibition with hydroalcoholic extract of Fibraurea tinctoria and Indomethacin were 67.6% and 68.49% respectively. We concluded that this study has established the anti-inflammatory activity of hydroalcoholic extract of Fibraurea tinctoria leaves. I believe the results justify the traditional uses of the plant in the treatment of wounds and inflammation.
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