Anti-Cancer Effect of Novel Hydroxy Flavons on Human Cancer Cell In vitro and In silico
Journal of Pharmaceutical Research International · pp. 193–199 · Published 28 Dec 2021
10.9734/jpri/2021/v33i61B35501Abstract
Anti-cancer effect of 7 hydroxy Favone and its derivatives were tested against human cancer cell lines such MCF-7 cell line using the in vitro by MTT assay in cancer cell lines. All the favones showed significant activity against all pathogens. 7-HF showed a maximum zone of inhibition against cancer cell lines. 7-try hydroxy flavones showed the lowest anti-cancer activity. And docking results shown as 7-HF has shown maximum docking -7.9, 7,8,3’-THF has -7.5 and 7,3’,4’ has -7.7. as per the results, 7 hydroxy flavone could be a possible source to obtain new and effective compounds to treat cancer.
Cited by 1
Francis Dhiya, K. S. Sindhu, J. Kavitha · In Silico Pharmacology · 2025
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