Anti-Bacterial Activity of Pigments Isolated From Pigment-Forming Soil Bacteria
Md. Mamunur Rashid, Md. Fakruddin, Reaz Mohammad Mazumdar, Fatema Kaniz, Md. Alimuddin Chowdhury
Journal of Pharmaceutical Research International · pp. 880–894 · Published 19 Feb 2014
10.9734/BJPR/2014/5148Abstract
Aims: Search for novel antimicrobials such as bacterial pigments is an issue of priority now. This study aims to isolate pigments with anti-bacterial activity from soil bacteria. Methodology: In this study, Pigment forming bacteria was isolated from soil samples collected from different sites of Dhaka city and its adjoining areas. Colonies of various colors such as yellow, golden yellow, red, pink, blue, green, purple and cream with both diffusible and non-diffusible pigments were isolated in pure cultures on nutrient agar plus 2 percent glycerol at pH 7.2 and 37ºC. Anti-bacterial activity of the pigments extracted from the bacteria were determined. Results: 15 pigment forming bacteria was isolated from soil and identified to genus level as Pseudomonas, Flavobacterium, chromobacterium, Xanthomonas, Aeromonas, Escherichia and Bacillus. All the pigments showed to be broad spectrum in terms of inhibitory activity against all the pathogens included in this study. Most of the pigments showed better anti-bacterial activity against gram-negative bacteria. Highest zone of inhibition was resulted by pigment no 15 against Salmonella typhi and lowest zone of inhibition was observed for pigment 13 against Staphylococcus aureus. Most of the pigments except four (pigment no- 3, 10, 12, 15) were found to be bacteriostatic to the test pathogens. MIC value of the pigments ranged from 1500-4000 µg/ml and most of the pigments showed lower MIC value against gram-negative organisms. Conclusion: On the basis of anti-bacterial activity and minimum inhibitory concentration (MIC) pigment form Aeromonas (no- 6), Escherichia (no-10) and Pseudomonas (no-15) can be selected as effective anti-bacterial agent. Further studies are needed to use these pigments in food, cosmetic and textile industries.
Cited by 33
S. Chaturwedi, Swostika Mainali, Richa Chaudhary · BMC Research Notes · 2024
A. Siegenthaler, Andrew K. Skidmore, G. D. de Groot · Plant and Soil · 2023
Soumya Nair, J. Abraham · Biologia · 2023
Yahya H. Shahin, Bassma H. Elwakil, D. Ghareeb · Biology · 2022
Şeymanur Çobanoğlu, A. Yazici · Current Microbiology · 2021
Abirami Pachaiyappan, Giji Sadhasivam, Mohan Kumar · 2020
Garima Bisht, Srishti Srivastava, Ritu Kulshreshtha · 2020
A. Sahar, Ibrahim Ghada S., Khalaf Maha I. al · International Journal of Pharma and Bio Sciences · 2020
Siddharthan N, Sandhiya R, H. N. · Asian Journal of Pharmaceutical and Clinical Research · 2020
R. M. Gulve, R. B. Deshmukh, Y. Phatake · Journal of Experimental Biology and Agricultural Sciences · 2019
Related research
- Bacteria Associated with Hospital Handrails in a Tertiary Institution in Nigeria — shares topic coverage
- The Impact of Microorganisms in Pregnancy — shares topic coverage
- Factors Affecting the Use of Probiotics during Antibiotic Therapy — shares topic coverage
- Evaluation of Multi-drug Resistant Bacteria and High Risk of Contamination in Ready to Eat Fruits in Kano Metropolis — shares topic coverage
- Survey and Identification of Bacteria and Fungi Associated with Two Dumpsites in Akure Metropolis — shares topic coverage
Article metrics
Real usage data collected on this platform.
18
Page views
0
PDF downloads
2
Outbound clicks
33
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.