An Overview on Leveraging Haplotype-based Genomic Selection for Precision Plant Breeding
B. P. Maruthi Prasad, M. Pallavi, B. V. Sinchana, J. Harish, K. Sainat
Journal of Advances in Biology & Biotechnology · pp. 19–32 · Published 25 Oct 2025
10.9734/jabb/2025/v28i113210Abstract
Haplotype-based genomic selection (GS) represents a transformative evolution in the field of precision plant breeding. This methodology integrates haplotypes defined as blocks of DNA variations inherited together with advanced genomic selection frameworks to improve the prediction of complex traits, such as yield and stress resilience. By capturing local epistatic interactions and reducing genotyping costs through efficient marker selection, haplotype-based Genomic selection enhances prediction accuracy and accelerates breeding cycles. This review discusses the foundational principles, methodologies, applications, and future prospects of haplotype-based Genomic selection, emphasizing its critical role in modern plant breeding programs aimed at addressing global food security challenges.
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