An Overview on Common Organic Solvents and Their Toxicity
Dirgha Raj Joshi, Nisha Adhikari
Journal of Pharmaceutical Research International · pp. 1–18 · Published 29 Jun 2019
10.9734/jpri/2019/v28i330203Abstract
Organic solvents are known as carbon-based solvents and their general property is primarily based on their volatility, boiling point, the molecular weight and color. Having enormous hazards associated with the organic solvents, they are used for millions of purposes which alert us to think more on its toxicity points. Almost all of the solvents are hazardous to health, if swallowed or inhaled more than the limit quantity and on contact to the skin most of them cause irritation. Some of the common solvents are acetone, ethyl acetate, hexane, heptane, dichloromethane, methanol, ethanol, tetrahydrofuran, acetonitrile, dimethylformamide, toluene, dimethylsulfoxide etc. Researchers, scientists, workers in the chemical industry and research institutes use these solvents on regular basis leading them to be affected in major aspects. But also, the nearby persons are affected by the contamination to the soil, water, air etc. If constantly exposed with solvents, it will badly affect the function of CNS and other body parts. The level of impact, sign and symptoms will depend on concentration, time, duration, frequency and nature of solvents, leading to common effects like headache, dizziness, tiredness, blurred vision, behavioral changes, unconsciousness, and even(Zimmermann, Mayer et al. 1985) death. To overcome it, the green chemistry concept is growing rapidly, and the solvent selection guide is in practice in many big company and research institute. A researcher or chemical worker is the primary person who works with solvents and they need to consider throughout these things while performing their activities for their own good health and for the sake of the world. The purpose of this review is to provide needed basic knowledge about common organic solvents and their potential toxicities which will alert researchers to think twice and always think for their health as well as for the environment via safe and green practice.
Cited by 560
Alaa Ewais, R. A. Saber, A. Abdel Ghany · SN Applied Sciences · 2023
Yijia Guo, Lihua Zhu, Liyin Zhang · Toxics · 2024
Wilson R. Tavares, Maria do Carmo Barreto, Ana M. L. Seca · Plants · 2021
Pengfei Cheng, Dong Wang, Peter Schaaf · Sustainable Energy & Fuels · 2024
Yaping Li, Linshang Zhang, Zhide Wang · Journal of the American Oil Chemists' Society · 2022
Delia Turcov, Madalina Paraschiv, Alexandra Cristina Blaga · Biomolecules · 2025
Soraya Rodwattanagul, Mathurada Sasarom, Pornthida Riangjanapatee · Drug Discoveries & Therapeutics · 2024
Jiabing Feng, Zhewen Ma, Zhiguang Xu · Chemical Engineering Journal · 2022
Juliana Lebeau, Thomas Petit, Mireille Fouillaud · Microorganisms · 2020
Azraul Mumtazah Razak, Siti Nor Asyikin Zakaria, Nur Fathiah Abdul Sani · Frontiers in Pharmacology · 2023
Showing 20 of 560 known citations — external sources report more than can currently be individually listed.
Related research
- Liver Profile of Artemether-lumefantrine-tinidazole in Healthy and Parasitized Mice — shares topic coverage
- Detection of Multiple Cry Genes in Bacillus thuringiensis Isolated from Different Soil Types in Zaria — shares topic coverage
- Bioavailability and Toxicity of Plastic Contaminants to Soil and Soil Bacteria — shares topic coverage
- Botulinum Toxin: A Friend or an Enemy? — shares topic coverage
- Inhibitory Effects of Phenolic Monomers on Methanogenesis in Anaerobic Digestion — shares topic coverage
Article metrics
Real usage data collected on this platform.
2
Page views
0
PDF downloads
0
Outbound clicks
560
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.