An In vitro Evaluation of Antidiabetic Activity of Alpinia galangal and Alpinia calcarata
V. Miss Revathi, G. Anuradha, S. Sumathy
Journal of Pharmaceutical Research International · pp. 28–35 · Published 14 Dec 2021
10.9734/jpri/2021/v33i57B34025Abstract
Background: The herbs, genus Alpinia calcarata and Alpinia galanga that underneath the family Zingiberaceae are rhizomatous and extremely aromatic. The study is to investigate the anti-diabetic activity of Alpinia galanga and Alpinia calcarata in-vitro. Material and Methods: The inhibitory effect of Alpinia galanga and Alpinia calcarata on α-amylase and α-glucosidase activities were evaluated. Results: The results revealed that both Alpinia galanga and Alpinia calcarata inhibited α-amylase and α-glucosidase activities in a dose-dependent manner (200–1000 μg/mL). However, Alpinia calcarata possess better antidiabetic activity than Alpinia galangal. Conclusion: The presence of phenolic and other phytochemical content in the herbs might be the reason for their ability to inhibit α-amylase and α-glucosidase activities. Thus, the drug formulating from the herbs, Alpinia galanga and Alpinia calcarata could be part of the potential alternative for synthetic anti-diabetic drug.
Cited by 5
Mohammed Wasim Ahmed, Safder Husain, Reesha Ahmed · Journal of Drug Delivery and Therapeutics · 2025
Dalia M. Rasheed, Mohamed A. Farag, Amira R. Khattab · Industrial Crops and Products · 2023
Showing 2 of 5 known citations — external sources report more than can currently be individually listed.
Related research
- Metal Based α-glucosidase Inhibitors: Synthesis, Characterization and α-glucosidase Inhibition Activity of Transition Metal Complexes — shares topic coverage
- Effect of Natural Products on Some Glycosidases and Their Expected Hypoglycemic Potential — shares topic coverage
- Synthesis, Characterization and α- Glucosidase Inhibition of Some Copper, Cobalt, Nickel and Zinc Complexes with N – Methylethylenediamine — shares topic coverage
- α-Glucosidase Inhibition and Glycemic Index of Chocolate Incorporated with Selected Spices — shares topic coverage
- Anti-Diabetic Activities of the Extracts from Euphorbia hirta L. (Euphorbiaceae) Specie found in Burkina Faso Using α-Glucosidase Inhibitor — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
5
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.