Aloevera Assisted Green Synthesis of Manganese Dioxide Nanoparticles and It's Antifungal Properties

Abstract

Manganese Dioxide (MnO₂) nanoparticles have garnered significant attention for their broad-spectrum antimicrobial properties, including antifungal activity. Aloe vera (Aloe barbadensis miller), a widely recognized medicinal plant, is rich in bioactive compounds such as flavonoids, phenolic acids, and polysaccharides, which possess reducing and stabilizing properties conducive to nanoparticle synthesis. The synthesized sample was characterized hy UV-VIS spectroscopy, FTIR, SEM etc. Biological testing demonstrated strong antifungal activity of these green-synthesized nanoparticles against harmful fungal strains such as Candida albicans and Aspergillus niger. The sugars, polyphenols and proteins present in aloevera suggests its stabilizing capability. The UV-Visible spectra at 320nm confirms the formation of MnO2 particles. FTIR Spectra peaks at 3213cm-1O-H stretching), 1622cm-1(C=C stretching), 1033cm-1 (C-O stretching) confirms the presence of phenols, flavonoids, polysaccharides respectively. The largest antifungal activity was observed in MnO2 NP suspension at 1000 ppm, which exhibited the maximum diameter of inhibition zone 57.667±1.528 mm as compared to the Thiram. The synthesized sample helps for future biomedical applications.