Determination of Some Haemotological Parameters in Children Infected with Plasmodium falciparum in Murtala Muhammad Specialist Hospital, Kano State, Nigeria

Abstract

Aim: The aim of the study is to determination of Some Haemotological Parameters in children infected with Plasmodium falciparum in Murtala Muhammad Specialist Hospital, Kano, Kano State, North Western Nigeria. Study Design: The study is analytic study. Place and Duration of the Study: In this research of the 350 children between the aged groups of 1-10 years infected with Plasmodium falciparum attending Murtala Muhammad Specialist Hospital Kano State were used for the study. Methodology: Malaria Rapid diagnostic kids (RDTs) kits were used for qualitative immunochromatographic flow tests in a dipstick (strip) or cassette forms that detect malaria antigen present in peripheral blood. Haemoglobin, Packed Cell Volume (PCV) and Reticulocytes count were determined using standard procedure. Results: A total of 350 subjects with Plasmodium falciparum, 190 (54.3%) male and 160 (45.7%) female with 100 control subjects both male and female were recruited in this study aged from 1 – 10 years. Relative distribution of 212(60.6%) and 138(53.8%) of the subjects were anaemic based on PCV and haemoglobin values respectively. It was also observed that 216(61.8%) with high reticulocytes and 134(38.2%) with normal value, while 0(0%) have lower value. However, the comparative mean value and standard deviation of female PCV, haemoglobin of Plasmodium falciparum patients and control were significantly reduced (P>0.05), while reticulocytes of Plasmodium falciparum patients and control were significantly high (P<0.05). Conclusion: In conclusion, the result indicated low PCV and haemoglobin among of male and female infected with Plasmodium falciparum because were significantly reduced (P>0.05) in patients and control, while reticulocytes of Plasmodium falciparum patients and control were significantly high (P<0.05).