Acute Oral Toxicity of a Herbal Gut  Function Modulator

Sunil Hajare; Ranjit Suresh Ingole; Sunidhi .; Ravikanth Kotagiri; Bhaskar Ganguly

doi:10.9734/cjast/2020/v39i430530

Research Article Open access CC BY 4.0

Acute Oral Toxicity of a Herbal Gut Function Modulator

Sunil Hajare, Ranjit Suresh Ingole, Sunidhi ., Ravikanth Kotagiri, Bhaskar Ganguly

Current Journal of Applied Science and Technology · pp. 58–61 · Published 26 Mar 2020

10.9734/cjast/2020/v39i430530

Abstract

The current study was designed to evaluate the acute oral toxicity potential of AV/AGP/30 (M/s Ayurvet Limited, Baddi, India) according to OECD 423 guidelines. AV/AGP/30 is a polyherbal gut function modulator in swine and poultry. Nine female Swiss albino mice were used for the study. Each animal served as its own control. Following the oral administration of the test substance, the animals were observed for manifestation of toxic effects and deaths. No toxic effects or mortalities were observed. The estimation of biochemical parameters (AST, ALT, ALP and creatinine) and histopathological studies also did not reveal any significant findings. Hence, AV/AGP/30 was found to be safe for use.

Acute oral toxicity AV/AGP/30 OECD 423 safety limit test

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Sunil Hajare, Ranjit Suresh Ingole, Sunidhi ., Ravikanth Kotagiri, Bhaskar Ganguly (2020). Acute Oral Toxicity of a Herbal Gut Function Modulator. Current Journal of Applied Science and Technology , 58–61. https://doi.org/10.9734/cjast/2020/v39i430530

Affiliations

Sunil Hajare — Department of Veterinary Pharmacology and Toxicology, PGIVAS, Akola, 444104, India.
Ranjit Suresh Ingole — Department of Veterinary Pathology, PGIVAS, Akola, 444104, India.
Sunidhi . — Research and Development Unit, Ayurvet Limited, Baddi, Himachal Pradesh, 173205, India.
Ravikanth Kotagiri — Research and Development Unit, Ayurvet Limited, Baddi, Himachal Pradesh, 173205, India.
Bhaskar Ganguly — Research and Development Unit, Ayurvet Limited, Baddi, Himachal Pradesh, 173205, India.

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