Acute Hepatic Insufficiency Disclosing Congenital Syphilis in a Neonate
M. A. Radouani, Y. Taboz, H. Benkirane, H. Aguenaou, M. Mrabet, A. Barkat
Journal of Advances in Medicine and Medical Research · pp. 1–11 · Published 11 Dec 2015
10.9734/BJMMR/2016/22286Abstract
Congenital syphilis is a maternal-fetal infection caused by Treponema pallidum. Early signs are characteristic skin lesions, lymphadenopathy, hepatosplenomegaly, failure to thrive, blood-stained nasal discharge, perioral fissures, meningitis, choroiditis, hydrocephalus, seizures, intellectual disability, osteochondritis, and pseudoparalysis (Parrot atrophy of newborn). We report the case of a new born on day 1 of life hospitalized for respiratory distress. Clinical examination showed signs of respiratory retraction with hypotonia. The assessment carried out revealed: severe liver insufficiency and infected cerebrospinal fluid (CSF) with sterile culture. The diagnosis of congenital syphilis in our patient was confirmed by a positive serology in the neonate and her mother. The outcome was fatal.
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