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Research Article Open access CC BY 4.0

A Review on the Therapeutic Management of COVID-19 Associated with Thrombotic Events and Coagulopathies

R. Vigneswaran, S. R. Senthil Kumar, T. Venkatachalam, P. Kalaiselvi, K. Sattanathan, R. Rajaguru, N. Srinivasan

Journal of Pharmaceutical Research International · pp. 98–105 · Published 26 Mar 2022

10.9734/jpri/2022/v34i27B36010

Abstract

Severe acute respiratory syndrome coronavirus two (SARS-CoV-2) is answerable for the coronavirus illness in 2019 (COVID-19) that chop-chop evolved from a virus in metropolis, Varied coagulopathies are rumored in association with COVID-19, together with disseminated intavasular action (DIC) sepsis-induced coagulopathy (SIC), native microthrombi, blood vessel occulation (VTE), blood vessels thrombotic complications and thrombo inflammation. There’s a overplus of publications and conflicting information on hematologic and astringent derangements in COVID-19 with some information suggesting the link to illness progress, severity and/or mortality. There is also growing evidence of potentially usefull clinical biomarkers to predict COVID-19 progression and illness outcomes of these, a link between blood disease and COVID-19 severity or mortality was instructed. During this opinion report, we have a tendency to examine the revealed proof of hematological and astringent laboratory derangements in COVID-19 and also the reticular SARS-CoV-2 evoked inflammation, with a focused discussion on blood platelet count alterations.

Thrombotic actions coagulopathies COVID-19 SARS-CoV-2 blood platelet count

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